Search results for " lentivirus"
Article
Dear lentivirus: We have not forgotten about you and how to improve your polishing recovery
Lentiviruses are commonly used for both chimeric antigen receptor (CAR) T cell therapy and ex vivo gene therapy.
Vector purification is very challenging due to low stability of these envel…
Article
Flexible Facilities for Viral Vector Manufacturing
There is less variability for lentivirus and gamma retrovirus that is used for virally genetically modified cell therapies (ex-vivo gene therapies); the scale is mostly 50 L and currently doesn’t go b…
Article
Scalable Viral Vector Manufacturing
However, as certain types of viruses such as Lentivirus for cell therapy and Adeno-Associated Virus for gene therapy become more common, there is a possibility for development of virus specific platfo…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
The most common viral vectors used in gene therapy are based on adeno-associated virus (AAV) and lentivirus. However, adenovirus and retrovirus are also of interest in this space (the latter being pri…
Article
Gene Therapies Push Viral Vector Production
By Feliza Mirasol
Several virus types have been studied for use as viral vectors in gene therapy, including adenovirus, lentivirus, retrovirus, and adeno-associated virus (AAV). Of these, AA…